Why less is worse for lupus

Why less is worse for lupus

Neutrophils need just enough copies of a gene for an antibody-binding receptor, say Willcocks et al. (page 1573). Whereas too few copies can contribute to lupus, too many can predispose to vasculitis. Cells can have as many as four copies of this gene, FCGR3B, which encodes the FcγRIIIb receptor, but some lupus patients have fewer than two. Willcocks et al. now find that this scarcity leads to ...

Children’s Associational Rights? Why Less Is More

Why Is Consumption Less Volatile Than Income?

Why Believe That There Is a God?

This article presents an argument for the existence of God, showing that the evident phenomena are best explained by supposing that a God causes them. The argument is based on the inductive force of four very evident general phenomena: that there is a physical Universe; that it is governed by very simple natural laws; that those laws are such as to lead to the existence of human bodies; and tha...

The knowledge paradox: why knowing more is knowing less

To provide an explanation of the evolution of scientific knowledge, I start from the assumption that knowledge is based on concepts, and propose that each concept about reality is affected by vagueness. This entails a paradox, which I term Knowledge Paradox (KP): i.e. we need concepts to acquire knowledge about the real world but each concept is a step away from reality. The KP provides a unify...